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In vivo the stiffness and
2018-11-14
In vivo, the stiffness and density of the surrounding ECM present an additional physical challenge to the moving cell body. Two principal mechanisms are known for moving cells to overcome these constraints: (i) proteolytic ECM degradation leading to gap widening and cell-generated trail formation an
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pkg inhibitor The MnO phase on the surface of high silica sa
2018-11-14
The MnO2 phase on the surface of high-silica samples is characterized by a mesh structure consisting of nanorods about 10–20nm in diameter and 500–700nm in length, chemically cross-linked with the CL surface. The MnO2 phase in low-silica samples consists of oval-shaped particles of 50–100nm, scatter
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br Declaration of Interests br
2018-11-14
Declaration of Interests Authorship Acknowledgments Introduction The main clinical problems of people living with HIV (PLWH) in areas with adequate healthcare standards and continued antiretroviral therapy (ART) supply are increasingly related to premature aging (Paiardini and Müller-Tru
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The findings of this meta analysis
2018-11-14
The findings of this Tyrosine Kinase Inhibitor Library meta-analysis should be interpreted with caution because of several limitations. First, we excluded conference abstracts, reviews, editorials, case reports and articles not written in English or Chinese, which may bias our results. In addition,
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The pooled results indicate relatively low
2018-11-14
The pooled results indicate relatively low diagnostic sensitivity of 0.70, and specificity of 0.83, suggesting a relatively high rate of missed diagnoses (30%) and misdiagnoses (17%). Likelihood ratios >10 and all trans retinoic acid from BALF correlates well with results from conventional immunocyt
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M tuberculosis has been considered innately resistant to
2018-11-14
M. tuberculosis has been considered innately resistant to β-lactam antibiotics, due to β–lactamase activity and the presence of non-classical transpeptidases in their cell wall (Hugonnet et al., 2009; Gupta et al., 2010). M. tuberculosis possesses a highly active β-lactamase, BlaC, that rapidly hydr
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Quercetin dihydrate br Methods The donor pig herd Auckland I
2018-11-14
Methods The donor pig herd (Auckland Island pigs; Living Cell Technologies, Manukau, New Zealand, and Diatranz Otsuka Ltd, Auckland New Zealand) was maintained in a designated pathogen-free facility and screened for an extensive panel of infectious agents including porcine endogenous retrovirus (
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br Funding Sources Research reported in this
2018-11-14
Funding Sources Research reported in this publication was supported by a grant from the Canadian Institutes for Health ResearchMOP-74493, the National Institute of Allergy and Infectious Diseases (NIAID) of the U. S. National Institutes of Health under Award Number R33AI098701, and the Intramural
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In total the selected model explained
2018-11-14
In total, the selected model explained 60% (se=8%) and 98% (se=9%) of the phenotypic variation in MDD and SDD, respectively (Fig. 3). Strikingly, the effect of the shared couple environment contributed as much as 14% (se=7%) and 22% (se=7%) of the phenotypic variance in MDD and SDD respectively. Fo
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The decrease in Ab levels is undoubtedly caused
2018-11-14
The decrease in Ab levels is undoubtedly caused by general deterioration of the immune response, which is well documented, not only in terms of decreased CD4+ T-cell counts but also in proliferative responses (Imami et al., 2013; Lewis et al., 2014). Here, we sought to quantify and characterize peri
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br Acknowledgements We are very grateful to
2018-11-14
Acknowledgements We are very grateful to Lindsay Cowell and Albert Goldfain for assistance with designing BCIDO. This work was conducted using the Protégé resource, which is supported by Grant GM10331601 from the National Institute of General Medical Sciences of the United States National Institu
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Brain imaging and genetic data alone
2018-11-14
Brain imaging (and genetic) data alone are insufficient for tracking trajectories in rotenone development. A significant time commitment must be made to the assessment of cognition and mental health. In the Saguenay Youth Study, for example, we have spent ∼8 h of the participant\'s time in these do
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While studies of depressed adults have begun to
2018-11-13
While studies of depressed adults have begun to tease apart the Sildenafil mesylate regions involved in self-reflection and negative rumination, few have investigated the connectivity of these regions to better understand self-referential processing network function. Task-dependent functional connec
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Introduction Mg Zn Re Zr
2018-11-13
Introduction Mg–Zn–Re–Zr alloy is a commonly used deformation magnesium alloy in aerospace industry because of its excellent properties, such as high-temperature strength, excellent corrosion resistance and anti-oxidation properties [1–6]. MgZn2, Mg2Y and Mg2La phases, as strengthening phase, are b
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Our selection of oxygen within
2018-11-13
Our selection of 10% oxygen within our gas mixture was informed by our prior studies in which we employed indwelling arterial catheters with simultaneous pulse oximetry to measure both partial pressures of arterial oxygen (PaO2) and hemoglobin oxygen saturation (SaO2) in rats exposed to hypobaric as
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