• ARB antihypertensive Composite soil samples were transported

  2025-02-08

  

  Composite soil samples were transported to the laboratory and then dried, crushed and passed through a 2mm sieve was. Sample digestion and release of elements method Sposito was performed [15]. Accordingly, taking into account soil moisture to 2g soil samples 12.5ml of nitric acid was added 4M. Samp

• Whereas more research is needed to identify the precise mech

  2025-02-08

  

  Whereas more research is needed to identify the precise mechanism by which FIN exerts its antidyskinetic effect, the substance p that it can negatively modulate dopaminergic transmission is also supported by our previous findings. Indeed, we have previously shown that FIN completely reversed the be

• Chronic inflammation is associated with both initiation and

  2025-02-07

  

  Chronic inflammation is associated with both initiation and progression of many neoplastic conditions [149], and ATX may be a player in the process. ATX/LPA signaling is positively correlated with the invasive and metastatic potential of several cancers including melanoma, breast cancer, ovarian can

• Another topic for research will be the

  2025-02-07

  

  Another topic for research will be the combination of other cytotoxic agents with Aurora kinase inhibitors. Particularly interesting might be the combination of Aurora kinase inhibitors and agents that depend on the spindle checkpoint for their activity, such as the taxanes, given the importance of

• br Antioxidant polymers conjugates Natural

  2025-02-07

  

  Antioxidant-polymers conjugates Natural antioxidants are usually used as a substitute for synthetics but some degradation phenomena could influence their applications. For example, ascorbic iwp2 as a natural antioxidant undergoes yellowish coloration as a result of oxidation [29]. Sing and Kapla

• Anticancer agent The PDZ domains of DLG interact with tumor

  2025-02-07

  

  The PDZ domains of DLG interact with tumor suppressor proteins, APC and PTEN, as well as with several viral oncoproteins such as the E6 protein present in oncogenic human papillomavirus (reviewed in [177]). It has been reported that overexpression of DLG in fibroblasts impairs the events in the G0/G

• Recent studies have supported the existence of an inward

  2025-02-07

  

  Recent studies have supported the existence of an inward RAS regulatory mechanism in which AT1 receptors downregulate angiotensin-converting enzyme 2 (ACE2) and subsequently impair angiotensin-(1-7) generation and MAS functionality (Jessup et al., 2006, Gallagher et al., 2008, Xia et al., 2009, Pern

• br Acknowledgements This work was supported by

  2025-02-07

  

  Acknowledgements This work was supported by Programme Grants from the MRC and the Wellcome Trust (SGC-C and MF). CB was in receipt of a Marie Curie Intra-European Fellowship during part of this work. We thank past and present members of our group for numerous valuable discussions throughout these

• br Conflicts of interest br

  2025-02-07

  

  Conflicts of interest Funding Introduction Brassicaceae is an economically important family of plants containing rapeseed, cabbage, broccoli, brussels, radish and mustard. Among them rapeseed plays a crucial role, because of its application in food and also in fuel industry. According to th

• br Regulation of AHR Activity AHR activity is regulated in

  2025-02-06

  

  Regulation of AHR Activity AHR activity is regulated in various ways. First, AHR protein levels are controlled via ubiquitin-mediated proteosomal degradation: Ligand binding induces AHR ubiquitination and subsequent degradation by the proteasome [5]. AIP, a component of the AHR chaperone complex,

• In summary the different types of interstitial cells found i

  2025-02-06

  

  In summary, the different types of interstitial cells found in the current study are illustrated in Fig. 7A (see legend for further details), which is suggestive of a heterogeneous complex network of interstitial cells communicating with each other. The possible signaling pathways involving this int

• In the isolated right atrium activation of muscarinic recept

  2025-02-06

  

  In the isolated right atrium, activation of muscarinic receptors and adenosine receptors may block the generation of action potentials in the sinoatrial node, inducing cardiac arrest (Fig. 1, Fig. 2, Fig. 3, Fig. 4, Fig. 5) (Camara et al., 2015, Campbell et al., 1989). Physiologically, this conditio

• Adenosine is an endogenous nucleoside that plays pivotal

  2025-02-06

  

  Adenosine is an endogenous nucleoside that plays pivotal roles in different physiological and pathophysiological processes by triggering specific cell-surface receptors both in the AZ20 and in the periphery. The adenosine receptors (ARs) are four different subtypes of G protein-coupled receptors (G

• Our published data showed that in mouse heart the

  2025-02-06

  

  Our published data showed that, in mouse heart, the protein level of WDR1 was highest during the embryonic stage, but became progressively decreased to a constant level from birth to adulthood (Yuan et al., 2014), indicating an important role of WDR1 in embryonic heart development. However, function

• The discovery of acetylsalicylic acid aspirin in paved the w

  2025-02-06

  

  The discovery of acetylsalicylic Alzheimer’s disease Aβ peptide (aspirin) in 1897 paved the way for the development of classical NSAIDs as first-line therapeutics for anti-inflammatory, anti-pyretic and analgesic therapy. Large efforts have been made in the following decades to improve the efficacy

16495 records 22/1100 page Previous Next First page 上5页 2122232425 下5页 Last page