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The paper is organized as follows http www
2020-04-27
The paper is organized as follows. Section 2 gives a brief presentation of the JPEG-LS algorithm and respective hardware implementation. In Section 3 the fault injection model and the simulation-based susceptibility analysis method are reviewed. Section 4 provides a discussion on the susceptibility
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In the current study we monitored different groups at
2020-04-27
In the current study, we monitored different groups at risk for CMV reactivation. Similar to the findings from other groups, we observed CMV-reactivations with high-level viremia mostly during the first three months after alloHSCT only in the (D−/R+) and (D+/R+) group [[23], [24]]. Increasing IFN‐γ
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Exogenous administration of POCs could
2020-04-27
Exogenous administration of POCs could theoretically inhibit breastfeeding [69]; however, the evidence in this review does not generally support a negative impact on breastfeeding outcomes. Studies examining the erk definition of POCs among postpartum women overall demonstrated no adverse effects o
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PGE EP activation has been found to
2020-04-27
PGE2-EP4 activation has been found to attenuate the activation of microglia and to prevent lipid peroxidation and pro-inflammatory gene expression in a murine model of lipopolysaccharide (LPS)-induced AGI-5198 inflammation [15]. Moreover, PGE2/EP4 signaling has elicited a protective function in redu
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Like all other cellular processes ubiquitination is also tig
2020-04-26
Like all other cellular processes, ubiquitination is also tightly regulated; more so, as myriads of pathways are controlled via this conjugation and dysregulation of ubiquitination has been implicated in various diseases including cancer [16], [17]. Quite a few of such regulatory mechanisms that con
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As small non coding RNAs microRNAs miRNAs can control
2020-04-26
As small non-coding RNAs, microRNAs (miRNAs) can control gene expression at the post-transcriptional level by binding to the 3′-untranslated regions (3′-UTR) of messenger RNAs (mRNA) [15], [16]. miRNAs have been anticipated to regulate virtually all cellular mechanisms [17] and to play an important
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Cell migration and invasion are central processes in the
2020-04-26
Cell migration and invasion are central processes in the development and metastasis of cancer. The regulation of cell migration by DDR1 has been reported in many types of cancer cell lines; however, conflicting results have been reported regarding the inhibitory as well as promotive effects of DDR1
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Materials and methods br Results
2020-04-26
Materials and methods Results Discussion Microbial production of trans-4Hyp, an added-value amino Dexlansoprazole australia for pharmaceuticals, offers significant advantages over conventional chemical extraction in economic and environmental aspects. However the low titer and productivity w
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Many PIM inhibitors have been reported to date however
2020-04-26
Many PIM inhibitors have been reported to date [7], [8], [9] however, none of them has been marketed so far. SGI-1776 is a representative first-generation PIM inhibitor, which had been under clinical trials for leukemia and prostate cancer [10]. While most of the first-generation PIM inhibitors are
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At first cartilage damage in osteoarthritis reflects the los
2020-04-26
At first, cartilage damage in osteoarthritis reflects the loss of proteoglycan and collagen network that increases the swelling of tissues. The incremented expression of DDR2 receptor has also co-related with the depletion of cartilage in surgically induced OA model [8]. Osteoarthritis, a degenerati
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R co localizes Golgi marker
2020-04-26
R co-localizes Golgi marker GM130 (Fig. 5). Our metabolic pulse-chase studies carried out in the presence of CSF-1 exposed the newly synthesized CSF-1R to its ligand, which promoted its rapid degradation. While this was clearly seen in control BMDMs, the mature band of CSF-1R remained intact for the
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br Materials and methods br Results br Discussion
2020-04-26
Materials and methods Results Discussion This study is the first to our knowledge that describes upstream cis-elements and transcription factors that are important for Crm1 expression and that drive its high expression in cancer and transformed cells. Using deletion and mutation analysis we
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br Acknowledgements br A subgroup of pediatric solid
2020-04-26
Acknowledgements A subgroup of pediatric solid neoplasms, collectively referred to as small round cell tumors (SRCTs) of childhood, demonstrates undifferentiated small round cell morphological characteristics. The SRCTs include neuroblastomas, lymphomas, and several bone and soft tissue sarcoma
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Although DGK is a lipid modulating enzyme the role of
2020-04-26
Although DGKγ is a lipid-modulating enzyme, the role of DGKγ in integral cell metabolism has not been reported. We found that DGKγ made a difference on cell metabolism profile in HCC cells, which may be caused partially by the downregulation of GLUT1. Glucose is a major source of energy, and decreas
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br Prospect of DDR antagonist DDR a receptor
2020-04-26
Prospect of DDR2 antagonist DDR2, a receptor of tyrosine kinase has been found now to be reported to play a significant role in onset of osteoarthritis at the early stage of diseases progression. The DDR2 are the receptor for extracellular collagen and activated upon the binding of collagen resul
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