• To our knowledge this study is

  2019-10-10

  

  To our knowledge, this study is the first to construct a whole-body transcriptome of D. variabilis. Most of the data currently accessible in NCBI are derived from a midgut EST database consisting of 1679 transcripts (Anderson et al., 2008) and about 20,000 mRNA sequences from the testis-vas deferens

• The most common adverse events

  2019-10-10

  

  The most common adverse events in relation to udenafil treatment are headache and facial flushing; other possible adverse events are febrile sensation, dyspepsia, and visual disturbances. No severe adverse event related to udenafil has been reported thus far. The adverse event rate recorded in the p

• Introduction Primitive neuroectodermal tumors PNETs are mali

  2019-10-10

  

  Introduction Primitive neuroectodermal tumors (PNETs) are malignant, small round cell tumors of neural crest origin which typically arises from bone or soft tissue in the trunk/axial skeleton/paraspinal regions in adolescents and young adults and comprises of 50% cases with local recurrence and met

• In addition to PGC transcriptional co

  2019-10-10

  

  In addition to PGC1α, transcriptional co-repressors such as NCOR and RIP140 participate in oxidative muscle remodeling induced by exercise, whereby reductions in their expression and the resulting de-repression of downstream TFs activates oxidative gene expression (Seth et al., 2007, Yamamoto et al.

• As a transcription factor HOXA regulates multiple

  2019-10-10

  

  As a transcription factor, HOXA9 regulates multiple target genes related to cell growth, including BRCA1 [34], BCL-2 [35], c-MYB [36], IGF1 [37], PIM1 [38] and so on. In addition, HOXA9 is a member of both activating and repressive transcriptional regulatory complexes, along with cofactor and collab

• 9184 br Materials and methods br

  2019-10-09

  

  Materials and methods Results Conclusion Conflict of interest Acknowledgements This work was supported by the National Key Research and Development Program of China (2018YFD0400302) and General Program of National Natural Science Foundation of China (31471602). Introduction A sign

• Several DA receptors heteromers with

  2019-10-09

  

  Several DA receptors heteromers with a therapeutic potential have been described, including D1R/D3R (Fiorentini et al., 2010), but their roles remain to be established. Moreover, most studies on receptor heteromers in addiction focused on the striatum because of its key role in the pathology and its

• Acidic substituents showed moderate biochemical activity

  2019-10-09

  

  Acidic substituents () showed moderate biochemical activity, but these compounds showed reduced cellular potency. Additional compounds bearing a carboxylic Asiatic acid pathway were also prepared and tested (data not shown). All of acidic compounds showed low cellular potency regardless of their bi

• Another important issue in biosensors is to

  2019-10-09

  

  Another important issue in biosensors is to design a simple and potable detection strategy to meet the requirement of the point-of-care (POC) test applications. According to the recent research, by using invertase uk5099 for hydrolyzing sucrose into glucose, the range of personal glucometer has been

• AG-490 and Soybean Glycine max is an important

  2019-10-09

  

  Soybean (Glycine max) is an important oilseed and can be a useful source of epoxy fatty acids (EFAs). This UFA contains an oxygen bridge across adjacent carbon atoms at single or multiple positions in the acyl chain, making them highly reactive and prone to cross-linking, and thus valuable industria

• In principle in vitro techniques for assessing enzyme induct

  2019-10-08

  

  In principle, in vitro techniques for assessing enzyme induction might include the use of cultured hepatocytes, precision-cut liver slices, immortalized Bradykinin acetate mass lines (such as those derived from hepatomas) and reporter gene constructs (where appropriate cells are transfected with re

• It has only recently been appreciated that antigen activated

  2019-10-08

  

  It has only recently been appreciated that antigen-activated Atglistatin kinase undertake two additional transient migrations during the early stages of T-dependent antibody responses. In the first of these, antigen-activated B cells migrate rapidly (within 2–3h) to the outer regions of the follicl

• In all available E E structures the

  2019-10-08

  

  In all available E2:E3 structures, the RING-type domain binds the E2 on a surface that is remote from the active site Cys (and therefore from the ubiquitin thioester) (Fig. 2). The non-contiguous E3-binding and active sites on the E2 imply that the role played by a RING to facilitate ubiquitin trans

• Structural changes within the heteromer induced by agonist

  2019-10-08

  

  Structural changes within the heteromer induced by agonist administration show a high level of complication. The presented results obtained in quantitative FLIM-FRET measurements with two selective ligands match the qualitative conclusions indicated by changes in the intracellular calcium level. The

• Keeping the cofactor content oligomeric state subcellular lo

  2019-10-08

  

  Keeping the cofactor content, oligomeric state, subcellular localization, and membrane association in view, DHODH has been broadly divided into two classes, class 1 and class 2 [26], [27]. In many species it is present to either cytoplasm (Class 1) or to the inner mitochondrial membrane (or plasma m

16407 records 978/1094 page Previous Next First page 上5页 976977978979980 下5页 Last page