• Several culture techniques have been

  2018-11-08

  

  Several culture techniques have been developed for ex vivo expansion of limbal epithelial cells, including those that used intact or denuded AM as a supporting matrix; adopted an airlifting technique to promote epithelial differentiation; and prepared 3T3 fibroblasts as feeder layers (Sun et al., 20

• order CMX001 br Experimental Procedures br Acknowledgments W

  2018-11-08

  

  Experimental Procedures Acknowledgments We are grateful to S. Yamanaka (University of Kyoto) for providing the plasmid and retroviral vectors through Addgene, and to T. Kitamura (University of Tokyo) for providing PlatE cells. We thank A. Nifuji, H. Ideno, and T. Kamada for helpful discussions

• Cyrano linc oip I Rik is a long intergenic

  2018-11-08

  

  Cyrano (linc-oip5, 1700020I14Rik) is a long intergenic ncRNA (lincRNA) transcribed in mouse ESCs (Chew et al., 2013; Guttman et al., 2010; Ulitsky et al., 2011) that was first characterized in zebrafish (Ulitsky et al., 2011). In zebrafish, it is a key regulator that functions in brain, eye, and nas

• br Acknowledgments br This work was supported by grants from

  2018-11-08

  

  Acknowledgments This work was supported by grants from the Juvenile Diabetes Research Foundation, Stanford Medical School Child Health Research Institute funded by the Stanford NIH/NCRR CTSA award number UL1 RR025744 and by the Lucile Packard Foundation for Children\'s Health (to NW), Arthritis

• In summary we confirm that HB F CD and HB

  2018-11-08

  

  In summary, we confirm that HB1.F3.CD and HB1.F3.CD.IFN-β best quality selectively migrated toward breast cancer cells. This is likely due to various chemokines expressed by the tumor cells and their cognate receptors expressed on the stem cells, such as SCF/c-kit and VEGF/VEGFR2, respectively. The

• In Raya et al found

  2018-11-08

  

  In 2009, Raya et al. found that somatic Quinacrine Dihydrochloride cost from FA patients could only be reprogrammed after correction of the genetic defect, suggesting an important role for the FA pathway in establishing pluripotency (Raya et al., 2009). However, Tulpule et al. subsequently created t

• The following are the supplementary

  2018-11-08

  

  The following are the supplementary data related to this article. Acknowledgments This work was supported by the Andrew L. Warshaw, MD Institute for Pancreatic Cancer Research, Massachusetts General Hospital, and by NIH-P01CA117969 to SPT. We would like to Thank Dr. Timothy Wang, Dorothy L. and

• niclosamide manufacturer The main drawback of NSC based

  2018-11-08

  

  The main drawback of NSC-based anti-tumor therapies is that, despite the effective tumor tropism exhibited by NSCs, only small portions of transplanted cells can migrate towards the tumor. Several recent publications have revealed that 70–80% tumor volume reduction can be achieved in various orthoto

• Overall ten genes five of which are coding genes

  2018-11-08

  

  Overall, ten genes, five of which are coding genes (FMOD, SULF1, COL12A1, STMN2 and MAEL), and five long-non-coding RNA (lncRNA) genes, were differentially expressed in hUC cells. lncRNAs are non-protein coding transcripts longer than 200 nucleotides. They have been implicated in the regulation of g

• We recently reported that iPSCs can be generated using non

  2018-11-08

  

  We recently reported that iPSCs can be generated using non-modified mRNA (Arnold et al., 2012). In this report we will focus on the crucial steps for successfully applying this method. Material and methods Results Discussion Acknowledgments The work was supported by funding from the Ger

• All iPSC derived neurons demonstrated expression

  2018-11-08

  

  All iPSC-derived neurons demonstrated expression of functional neurotransmitter receptors, responding to glutamate/glycine, GABA and to a lower extend to acetylcholine. Interestingly, the neuronal cultures also developed synchronized spontaneous calcium oscillations, which were likely to reflect met

• br Resource table Resource details The

  2018-11-08

  

  Resource table. Resource details The study was approved by the Singhealth ethics committee (protocol number SHSIBC-2014-031), and written informed consent was obtained from the patient. 2ml of peripheral blood sample was obtained from a male 64-year-old Parkinson\'s disease patient carrying a he

• The numbers of GFAP NSCs did not return

  2018-11-08

  

  The numbers of GFAP+ NSCs did not return to control levels at even the longest survival times examined (approximately 1 month after AraC and GCV treatment). One possible explanation for this is that we simply did not wait long enough to observe the complete return to control values. Alternatively, t

• Importantly this recent paper Gonzalez Cordero

  2018-11-08

  

  Importantly, this recent paper (Gonzalez-Cordero et al., 2013) together with our work confirms the capacity of pluripotent stem cells to provide a renewable source of cells to produce photoreceptors in vitro and highlights the great interest of using the 3D culture system developed by Sasai’s group.

• br Experimental Procedures Detailed Experimental Procedures

  2018-11-08

  

  Experimental Procedures Detailed Experimental Procedures are provided in the Supplemental Experimental Procedures. Author Contributions Acknowledgments Introduction For an adequate quantitative production of each blood cell lineage in homeostasis and in stress conditions, the fate of he

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