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order Cisplatin br Acknowledgement br Introduction The reaso
2018-11-06
Acknowledgement Introduction The reason why leadership maters a lot in organizational behavior studies is evident from the fact that, since 2000, organizations have spent $50 billion per year on the leadership development (McCallum & Connell, 2009). Recent studies also indicated an increase in
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The most significant characteristic of active
2018-11-06
The most significant characteristic of active learning is student involvement: students are actively engaged in individual or group activities during the class session, these may include reading, discussing, commenting, and exploring tasks, ideas and theories (Liebman, 1997). Rather than declamatory
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This factor along with peristaltic hypofunction associated w
2018-11-06
This factor, along with peristaltic hypofunction associated with diabetic autonomic neuropathy, may lead to raised intraluminal pressure, allowing the gas-producing bacteria to invade the colonic mucosa through mucosal breaks, forming pneumocysts. Histologically, the cysts of pneumatosis cystoides
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SSEH is typically associated with a more
2018-11-06
SSEH is typically associated with a more favorable prognosis than is spontaneous spinal subdural hematoma, which can be caused by the use of anticoagulants or pre-existing vascular lesions. The excision of a vascular lesion can cause ischemia, resulting in a less favorable surgical outcome than for
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Among six pluripotency regulators examined only NANOG and
2018-11-06
Among six pluripotency regulators examined, only NANOG and POU5F1 were downregulated by 2days of LY364947 treatment, which impaired DE competence. NANOG is a direct target of Nodal/Activin signaling, and the maintenance of its expression requires active Nodal/Activin signaling (Xu et al., 2008; Cham
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buy Erismodegib In our evaluation of the G q PLC PKC
2018-11-06
In our evaluation of the Gαq-PLCβ-PKC pathway, treatment with agonist (kisspeptin), or a negative allosteric modulator (MPEP) of specific Gα-q/11-coupled GPCRs had no significant effects on either total cell growth/viability or undifferentiated hESC renewal, despite detection of transcripts encoding
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Previous reports have suggested that WNTs modulate
2018-11-06
Previous reports have suggested that WNTs modulate BMP signaling by promoting C-terminal phosphorylation of SMAD1/5, key components of the BMP signal transduction pathway (Fuentealba et al., 2007). Therefore, we compared the phosphorylation of SMAD1/5 in EBs formed in the combination of WNT3A/BMP4 t
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br Results br Discussion We have demonstrated that
2018-11-06
Results Discussion We have demonstrated that the hPSC-derived HBCs could be maintained on a human LN111-coated dish in an integrin α6- and β1-dependent manner (Figure 1). It is known that undifferentiated hPSCs could be maintained on a human LN511-coated dish but not on a human LN111-coated di
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Previously LSD was identified as a
2018-11-06
Previously, LSD1 was identified as a miR-137 target in the neural stem hematoxylin of embryonic brains (Sun et al., 2011b) and in colorectal cancer cells (Balaguer et al., 2010). The interaction between miR-137 and LSD1 has been shown to play a critical role in the molecular circuitry controlling ne
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It is interesting to note that
2018-11-06
It is interesting to note, that in utero lethality in FAH−/− pigs, which is correctable by NTBC, provides unique opportunities to study regenerative therapies targeted to the fetus (MacKenzie et al., 2002). As liver injury can be initiated by stopping NTBC at any time in development, FAH−/− pigs cou
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elastase br Results br Discussion In the present study
2018-11-06
Results Discussion In the present study, we have developed a unique stem cell line from preimplantation mouse blastocysts using culture conditions that support development and maintenance of mouse EpiSCs or human ESCs (Brons et al., 2007; Tesar et al., 2007; Greber et al., 2010). Growth factor
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br Cardiac tissue macrophages Cardiac tissue macrophages
2018-11-06
Cardiac tissue macrophages Cardiac tissue macrophages (cTMs), which are found in abundance in the murine heart (Fig. 1), display typical macrophage characteristics, undertaking extensive macropinocytosis and phagocytosis to sample the local microenvironment and express a wide array of PRRs such a
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br Materials and methods br
2018-11-06
Materials and methods Results Discussion This present study and previous works in the literature have shown that mechanical stimulation promotes the proliferation of BMSCs (Luu et al., 2009). In this study, the presented results revealed that pressure promoted BMSC proliferation by facilita
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Progress in the field of neuronal replacement using
2018-11-06
Progress in the field of neuronal replacement using NT2 committed to differentiate with retinoic Cy5.5 hydrazide (RA) is limited by the long time frame necessary to generate postmitotic NT2N neurons and also by the low proportion of terminally differentiated neurons. Thus, neuronal differentiation
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br Acknowledgments This work was supported by grants of
2018-11-06
Acknowledgments This work was supported by grants of the Basque Government (GIC/IT-589/13, SAIOTEK S-PE11UN124-125 and DKR-2012-59 to A. R.), the University of the Basque Country (UPV/EHU 243/2011 to I. G-B.), and the Instituto de Salud Carlos III, Centro de Investigación Biomédica en Red de Salu
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